| Business Name | Location | Phone | Owner | Approx Dates of Existence |
| A. B. Hausser The General Grocer | Corner of Vine Street and Railroad Avenue | 6-J | A. B. Hausser | 1913 |
| A. Chilton, Freight Carting | Stockton Street | 1913 | ||
| A. Dughi, dealer in Fruits, Confectionery, Nuts, Cigars, and Tobacco | Railroad Avenue | 36-J | 1913 | |
| A. Sell's 5 & 10 Cent Store | 104 | 1945 | ||
| A. W. Conover Electric Company | Railroad Avenue | 51 | 1926 | |
| Adam Kullmar, Barber | West Railroad Avenue | Adam Kullmar | 1896-1913? | |
| Albert Kienzle, Heating | Buckelew Avenue | Albert Kienzle | 1896 | |
| Allied Appliance Co. | East Railroad Avenue | 52 | 1945 | |
| American Stores Co. | East Railroad Avenue | 1926 | ||
| Angelo's Barber Shop | Railroad Avenue | |||
| B. Casser & Co., Flour, Grain, Hay, Feed | 1913 | |||
| B. D. Davison Lumber Yard | Gatzmer Avenue | 12 | 1892-1923 | |
| Bill's 301 Ranch | Buckelew Avenue | 1945 | ||
| Bohinski's Market | E. Railroad Avenue | 1-0074 | 1948 | |
| Brookcrest Farm | 267 | E. Gerner and G. M. Seaton, Prop. | 1945 | |
| Brower's Bakery | Railroad Avenue | 1913 | ||
| Busco Bros. Metered Fuel Oils, Kerosene, Gasoline, and Motor Oils | 145 Buckelew Avenue | 1-0248 | 1945-present | |
| C. A. Linke, Wells Dug & Cleaned | Forsgate Drive | 1-0324-M | 1948 | |
| C. H. Horlos, Ranges Stoves, and Heaters; Plumbing, Heating, and Tinning | Buckelew Avenue | 31-M | 1913 | |
| C. M. Davison, General Store | Lower Jamesburg | 1898 | ||
| C. Pellino, Custom Tailor | W. Railroad Avenue | 1948 | ||
| Carl Neeff, Florist | Buckelew Avenue | 1913 | ||
| Central Cigar Store | Next to Post Office | Wm. S. Hankins, Prop. | 1913 | |
| Chamberlin & Barclay, Dealers in Hay, Straw, Grain, Potatoes, Etc. | 1913 | |||
| Clarence W. Patten, Taxi, Cars for Hire | Corner of Railroad Avenue and Church Street | 103 | 1925 | |
| Colletti's Barber Shop | W. Railroad Avenue | 1948 | ||
| Collins Bros. Texaco Service, Western Auto Associate Store | Gatzmer Avenue | 1-0003 | 1948-1952 | |
| Condit M. Davison, Insurance and Real Estate | Corner of West Church Street and Gatzmer Avenue | Condit M. Davison | 1913 | |
| Cornelius Mount, Market | Willow Street | 1881-1898? | ||
| Cottrell Printing Co. | Front Street | 1948 | ||
| D. Rhodes & Bro., Carpenter and Builder | 16-F-5 | |||
| Daniel M. Clark, Jeweler | 9, 1-0200 | 1909-1947? | ||
| Davies Florist | 111 Buckelew Avenue | 1-0228 | 1948-present | |
| DeLuxe Cleaners | W. Railroad Avenue | 1-0421 | 1948 | |
| Di Gangi's Market | W. Railroad Avenue | 1-0060 | J. Di Gangi | 1945-1951 |
| Downs & Finch Shirt Factory | West Railroad Avenue | 1871-1889 | ||
| Dr. Edward C. Galsgie, Health Home | Buckelew Avenue | 1913 | ||
| Dr. Lawrence M. Lief | Gatzmer Avenue | 1945 | ||
| E. S. Hammell, Printer, Jamesburg Record | W. Railroad Avenue | E. S. Hammell | 1892 | |
| E. Snedeker, Butcher | Stockton Street | E. Snedeker | 1892 | |
| E. W. Snedeker, Carpenter | Corner of Railroad Avenue and Vine Street | 1895 | ||
| Eddie and Johnnie Gulf Service | Lincoln Avenue | 1-9857 | 1951 | |
| Edward Dock, Jamesburg Livery | ||||
| Edward J. Clinton & Son, Contractors of Painting, Decorating, Sign and Scenery Work | P. O. Box 426 | 18-M | ||
| Edward Warshany, Painting & Paper Hanging | Sedgwick Street | 1-0144M | 1948 | |
| Elias S. Bennett, Jr., Fish, Oysters, and Clams in Season | Lower Jamesburg | 15-M | 1913 | |
| Elias Z. Bennett, dealer in electric, telegraph, telephone poles, oak piling | 15-M | 1913 | ||
| F. C. Borden, Jr., Real Estate and Insurance | Hausser Building | 1913 | ||
| F. H. Pownall, Hay, Straw, and Grain | Frank H. Pownall | 1892 | ||
| F. W. Eulner, Wholesale Butcher, Drover, and Shipper | Augusta Street | 1895 | ||
| Frank H. Pownall Iron Works | 1913 | |||
| Frank Herche, Custom Taylor | P.O. Box 83 | 1913 | ||
| Frank Jennings, Slate Roofer | Corner of E. Railroad Avenue and Augusta Street | Frank Jennings | 1892 | |
| Frank Paul's Bar | Hooker Street | 1-0080 | 1945-1948 | |
| Frank Paul's New Bar | E. Railroad Avenue | 1-0080 | 1951 | |
| Frank Richiusa, First Class Barber | East Railroad Avenue, Between Augusta and Vine Streets | 1913 | ||
| Frank's Café | Gatzmer Avenue | 1-0280 | 1948-present | |
| Fred Greismans Grocery | 1913 | |||
| Fred Nodocker, Fine Groceries, Confections, Fruits, Tobacco, and Cigars | Buckelew Avenue | Fred Nodocker | ||
| Gabriel & Christie's Garage | Corner of Railroad Avenue and Hooker Street | 126 | 1945 | |
| Geo. McD. Mount & Son, Wheelwrights and Blacksmiths | Upper Jamesburg | Formally Chas. S. Brown | 1895 | |
| George F. Willan, Plumbing & Heating Contractor | Buckelew Avenue | 1-0495 | 1948 | |
| George M. Davison, Mason and Contractor | P.O. Box 41 | 1913 | ||
| George Simonson, Manufacturer of Light and Heavy Carriages and Wagons | Corner of Willow Street and Gatzmer Avenue | 1898 | ||
| Gilbert D. Soden, Contracting Mason | Willow Street | Gilbert D. Soden | 1896 | |
| Giuseppe Craparotta, Butcher | Lincoln Avenue | 1913 | ||
| Grace Ann Beauty Shoppe | 1-0201 | 1948 | ||
| Gray Block Co. | W. Railroad Avenue | 1-0580 | 1952 | |
| Gray-Rock Block Company | W. Railroad Avenue | 1-0580 | 1951 | |
| H. A. Edwards, Agent for Oliver Typewriters | 7-R | 1913 | ||
| H. D. Maze Department Store (Formerly J. Mazursky) | 55 Railroad Avenue | 1-0204 | H. D. Maze | 1947 |
| H. D. Zandt, M. D. | Railroad Avenue, above Church Street | H. D. Zandt | 1892 | |
| H. G. Harpootlian & Son, Department Store | West Railroad Avenue | 222 | 1945 | |
| Harry E. Heckman, Groceries, Fruits, and Vegetables | Lincoln Avenue | 1913 | ||
| Harry Gildar's Paradise Club | 1-0206 | 1951 | ||
| Harry L. Hubbs, Plumbing, Steam, and Hot Water Heating | Gatzmer Avenue | 111 | 1925-1926 | |
| Henry J. Dobenski, Ice | 6 | 1945 | ||
| Henry Wetzel & Sons, Distributors of Vitality Feeds | 1945 | |||
| Horace Brown, Wheelwrighting, Blacksmithing | 1898 | |||
| Hutchinson and Matlack: Coal, bull brand feeds, hay, dexter cement, plaster, roofing, etc. | 138 | 1926 | ||
| Ideal Frocks | Railroad Avenue | |||
| Intravartolo's Market | E. Railroad Avenue | 1-0178 | 1923-early 1990s | |
| J. & J. Service Station, Inc. | Gatzmer Avenue | 1-0376 | James Tilton, John Labanak | 1948 |
| J. C. Magee & Son, Lumber, Coal, Furniture | Upper Jamesburg | Joseph C. Magee | 1892 | |
| J. C. Magee, Agent for Farmers' Mutual of Salem County, N.J. | Railroad Avenue | Joseph C. Magee | 1898 | |
| J. E. Marryott, Commissioner of Deeds and Notary Public | 1913 | |||
| J. L. Hulse, Monuments & Markers | ||||
| J. L. Suydam, A. M., M.D. | Church Street | J. L. Suydam | 1896 | |
| J. P. Coffey, Pumbing, Tinning, Heating | 1913 | |||
| J. R. Wilson and Son, Ice Dealers | 50 | J. R. Wilson | 1926 | |
| James Emens, Carpenter and Builder | Upper Jamesburg | 1898 | ||
| Jamesburg Battery Shop | 1945 | |||
| Jamesburg Bee Hive and General Store | Corner of Railroad and Buckelew Avenues | 1898 | ||
| Jamesburg Cornet Band | J. M. Owens, Director | 1913 | ||
| Jamesburg Drug Store | Edith C. Schwartz, Ph. C. | 1926 | ||
| Jamesburg Electric Company | Joseph W. Pharo | 1913 | ||
| Jamesburg Hardware Co. | Gatzmer Avenue | 12, 1-0012 | Clayton Family | 1925-present |
| Jamesburg Home Bakery | J. Messner, Prop. | 1926 | ||
| Jamesburg Hotel | Gatzmer Avenue | 28-W | Alex Ballantyne, Prop. | 1913 |
| Jamesburg Laundry | Corner of Railroad Avenue and Buckelew Ave (Forsgate) | Mrs. John Monahan | 1896 | |
| Jamesburg Market | F. W. Eulner, Prop. | 1898 | ||
| Jamesburg Mens Shop | 4 Hooker Street | 1-0351M | 1948 | |
| Jamesburg Men's Shop | Hooker Street | Anthony Collura | 1947 | |
| Jamesburg Press | 1951 | |||
| Jamesburg Shirt Factory | West Railroad Avenue | William C. Crosby | early 1900-1913 | |
| Jamesburg Shoe Company, Inc. | 1913 | |||
| Jamesburg Steam Laundry | Corner of Forsgate Drive and West Railroad Avenue | John Monahan, Prop. | 1913 | |
| Jamesburg Sweet Shop | W. Railroad Avenue | 1-0782 | Pete and Larry Collura, Prop. | 1945-1952 |
| Jamesburg Used Car Center | Buckelew Avenue | 1-0441 | J. E. Smith, N. Collura | 1951 |
| Jamesburg Water Company | Joseph W. Pharo | 1913 | ||
| Jamesburg Wine & Liquor Store | 49A East Railroad Avenue | 1-0118 | David B. Metz, Prop. | 1945-1951 |
| Jaques & Harlos, Dealers in Bicycles | Buckelew Avenue, below the bank | 1895 | ||
| Jaques' Drug Store | Railroad Avenue, Post Office Building | 1892-1896? | ||
| Jennie A. Elliott, Milliner | Railroad Avenue | Jennie A. Elliott | 1892 | |
| John B. Soden, Contractor and Builder | John B. Soden | 1913 | ||
| John Brognard, Wheelwrighting, Blacksmithing | Stockton Street | 1898 | ||
| John Dingfeld, Horseshoeing and General Blacksmithing | Near Foundry, Jamesburg | John Dingfeld | 1913 | |
| John Erhart, Men's Shoes, Groceries, and Provisons | Sherman Street | John Erhart | 1892-1913 | |
| John H. Herche & Rowland D. Oliver, General Insurance | 1-0212, 1-0034 | 1951 | ||
| John H. Herche, Insurance | Railroad Avenue | 1-0212 | John H. Herche | 1945-1948 |
| John. P. Kirkpatrick, Counsellor-at-Law | 1913 | |||
| Joseph Baumgartner, Pumbing, Tinning, Heating, and Gas Fitting | 8-M | 1913-1925 | ||
| Joseph H. Scranton for Forsgate Farms Dairy Products | 1-0224 | 1951 | ||
| Kerr Chickeries, Inc. | Lake Street | 65 | C. A. Miller, Manager | 1945 |
| Kerr's Butter Scotch | Buckelew Avenue | 1945-1948 | ||
| Kip's Liquor Store | 1-0211 | 1948 | ||
| Koblenzer & Dazien Shirt Factory | West Railroad Avenue | 1889-July 1901 | ||
| L. R. Cheespman, Photo-Artist | L. R. Cheespman | 1892 | ||
| L. T. Bennett & Son People's Public Market | Railroad Avenue | Ernest Bennett, Manager | 1913 | |
| L. T. Bennett General Store | Gatzmer Avenue | 1913 | ||
| Lake Diner, The | Forsgate Drive | 287 | 1945 | |
| Lakeside Diner and Grocery | Forsgate Drive | 1-0287, 1-0497 | 1948 | |
| Lange's Hall | Hooker Street, P.O. Box 134 | Otto Lange | 1913 | |
| Lange's Ice Cream Parlor | Railroad Avenue | 29 | A. E. Lange | 1913-1926? |
| Larry Intravartola, Plumbing & Heating | 1-0176 | 1948 | ||
| Leon & Eddie's Sunoco Service | Lincoln Avenue | 1-9857 | 1951 | |
| Lewis Goldstein, D.D.S. | W. Railroad Avenue | 1-0294 | 1948 | |
| Liberty Theatre | 1913 | |||
| M & N Contractors | 37 Forge Street | 1-0472 | 1951 | |
| M. Jorgoran, Painting, Decorating, and Paper Hanging | Gatzmer Avenue | M. Jorgoran | 1926 | |
| M. W. Construction Co. | Grand Street | 1-0286 | 1948 | |
| Marisi's Grocery | E. Railroad Avenue | 1-0399M | 1947?-1951? | |
| Matlin Cleaners | 16-18 Willow Street | 1-0329 | 1948 | |
| Mazursky's Department Store | 1-0204 | H. D. Maze, Manager | 1948 | |
| Mc Carty's Dairy, Dealers in Forsgate Farms Products | Gatzmer Avenue | 1-0067 | 1951 | |
| Michael D. Santoro, Custom made boots and shoes | West Railroad Avenue, near Post Office | 1913 | ||
| Monroe Wikoff Grain Elevator Company | West Railroad Avenue | 6L | 1913 | |
| Mounts Grocery | Railroad Avenue and Hooker Street | 74 | 1945 | |
| Mrs. William H. Brooks, Insurance | 1-0033 | 1951 | ||
| Nap's Bar and Grill | Forsgate Drive | 1-9853 | 1947?-1952? | |
| New York Bargain Store | Railroad Avenue, below Willow Street | B. Goldstein, Prop. | 1913 | |
| Nick Rollinger, Painter and Decorator | Gatzmer Avenue | 1948 | ||
| Nisonoff's Market | E. Railroad Avenue | 1-0237 | 1926-1948 | |
| O. Chaitin's, Clothing, Dry Goods, Millinery, and Human Hair Goods | Railroad Avenue, Between Augusta and Vine Streets | 1913 | ||
| Oliver L. E. Soden Real Estate & General Insurance | W. Railroad Avenue | 1-0001 | Oliver L. E. Soden | 1929-present |
| Palmer's Meat Market | Railroad Avenue | Lester J. Palmer, Prop. | 1925 | |
| Park Tavern | Lincoln Avenue | 1-0279 | Mrs. Veronica Yesaitis, Prop. | 1948-present |
| Paxton & Buckelew, Dry Goods, Dress Goods | Upper Jamesburg | Paxton and Buckelew | 1892 | |
| Paxton & Co. | Upper Jamesburg | 1896 | ||
| Peach Nursery | George A. Shultz | 1872-1892? | ||
| Perrine & Buckelew Incorporated | Gatzmer Avenue | 39, 4 | 1913 | |
| Perrine & Buckelew Lumber Co. | Gatzmer Avenue | 1-0040, 1-0041 | 1866-1926? | |
| Perrine's Confectionery | 63 E. Railroad Avenue | 1-0211, 278 | 1945-1951 | |
| Perrine's Garage, Inc. | Railroad Avenue | Wm. Perrine, Fred Perrine | 1930?-1990? | |
| Perrine's Pontiac Inc. | 200 Buckelew Avenue | 1-0107 | 1948 | |
| Perrine's Wine and Liquor Store | 211 | 1945 | ||
| Peter P. Bennett Popular Grocer | Below the First National Bank | 1913 | ||
| Pine Tree Farm | 19F3 | 1913 | ||
| Pineland Incubator and Brooder Company | 1893-1903 | |||
| Piorkowski Grocery Store and Taxi Service | Gatzmer Avenue | 1-0203 | 1951 | |
| Popular Milliner | Corner of Stockton and Sheridan Streets | Jennie E. Bayles | 1913 | |
| Quality Bakery | E. Railroad Avenue | 1-0056 | Edward Mendoker, Prop. | 1932-present |
| Quick Lunch and Ice Cream Parlors | Scarlett Building | Mrs. J. M. Danser, Prop. | 1895 | |
| R. & S. Radio | 29 Lincoln Avenue | 1-0083 | E. Rabbe, R. Sabatino | 1951 |
| R. G. Davison Concrete Products | West Railroad Avenue and Front Street | 77 | 1925 | |
| Raritan Valley Farms, Inc. | W. Railroad Avenue | 1-0471-J | Ed Yanek, Distributor | 1951 |
| Reach Sporting Goods | Hooker Street | Miss Margaretha M. Lange | 1913 | |
| Red & Black Auto Wreckers | Lincoln Avenue | 1-0171 | 1948-present | |
| Red Front Grocery | Next to Drug Store | Martin F. Kelly, Richard Lewis, Jr. | 1896 | |
| Reid & Clark, Car Dealer | 9 | 1913 | ||
| Reid Brothers, Body and Fender Service | 1-0004, 1-0139 | 1948 | ||
| Robbins' Fire Proof & Steam Heated Garage | Next to First National Bank, Lower Jamesburg | 18-M | 1913 | |
| Robert M. Cole, Carpenter and Builder | Robert M. Cole | 1896 | ||
| Rose's Beauty Shop | 138 | 1945 | ||
| Route's Auto Body and Fender Works | Lincoln Avenue | 1-9856 | 1951 | |
| Sam Tuminaro, Macarioni, Groceries and Tinware | Helmetta Road, East end Sedgwick Street | 1913 | ||
| Samuel Marryott, Justice of Peace, Collection Agent | Samuel Marryott | 1892 | ||
| Shapanka Dress Co. | Hooker Street | 1948 | ||
| Shapanka's Express | Buckelew Avenue | 1948 | ||
| Shavinsky's Department Store | 1-0399W | 1948 | ||
| Southgate Pharmacy | Railroad Avenue & Willow Street | 1945 | ||
| Spezio's Market | W. Railroad Avenue | 1-0216 | 1926-1948 | |
| Star Theatre | W. Railroad Avenue | 1-0368 | 1948 | |
| Stardust Soda Shoppe | Star Theatre Building, West Railroad Avenue | 1-0356, 1-9854 | John Meyer, Prop. | 1948 |
| Stonaker & Harvey, Wholesale Dealers in Grain, Flour, Hay and Feed | 67 | H. C. Stonaker and J. E. Harvey | 1925 | |
| The Center Department Store | E. Railroad Avenue | JA-0543 | ||
| The Ferris Seed Company | East Railroad Avenue | 167 | 1945 | |
| The First National Bank of Jamesburg | Buckelew Avenue, later West Railroad Avenue | James Buckelew | 1913 | |
| The Frank B. Jolly Printing Co. | 1913 | |||
| The Friendly Liquor Store | 63A E. Railroad Avenue | 1-0559 | S. "Tom" Berkowitz | 1951 |
| The Jamesburg Bakery | Willow Street | Fred Nodocker | ||
| The Jamesburg Garage | W. H. Quackenbush, Manager | 1913 | ||
| The People's Meat Market | Willow Street | 15-W | Cornelius Mount, Prop. | 1881-1913? |
| The R. Lewis Furniture Company | West Railroad Avenue | R. Lewis | 1909 | |
| The Red Front Cash Grocery | R. Lewis, Jr., Prop. | Late 1800s | ||
| Tilton's Sea Food | Railroad Avenue | 1-0087 | O. V. Tilton | 1945-1948 |
| Tom's Liquor Store | Hooker Street | 1-0088 | 1951 | |
| Tucker Sales and Services | E. Railroad Avenue | 1-0126 | Gabriel & Christine | 1948 |
| Van Dyke & Conover Lumber Co. | 7-M | 1913 | ||
| Van Liew Motors Inc. | Lincoln Avenue | 1-0260 | 1951 | |
| Walker's Confectionery | E. Railroad Avenue | 1-0278 | 1947?-1948? | |
| Wally's Photo Shop | West Railroad Avenue | 1945 | ||
| Websters Grocery | Buckelew Avenue | |||
| Weinraub's Drug Store | E. Railroad Avenue | 1-0198, 1-0240 | S. Weinraub, PhG | 1945-1948 |
| Will H. Baum Studio of Music | Gatzmer Avenue | Will H. Baum | 1926 | |
| William H. Brooks, Fire Insurance | William H. Brooks | 1913?-1926? | ||
| William H. Courter, Insurance | William H. Courter | 1892 | ||
| William R. Dey, Taxi Service | Gatzmer Avenue | 27 | William R. Dey | 1926 |
| WM. E. Paxton, Justice of Peace and Commissoner of Deeds | 1913 |